Migraine headaches originate when an overload of serotonin causes the diameter of blood vessels leading to the brain to dilate, and get wider in the brain. Consequently, blood flow increases, and pain receptors in the vessels are stretched, which leads to the excrutiating pain associated with a migraine headache (Borne, 1998; others). In numerous tests and studies though, negative ion treatment has proven to prevent the overproduction of serotonin, and therefore the subsequent migraine headaches (Kreuger, 1957; Soyka, 1991; Sulman, 1974).